Endocrine Abstracts

Determining the sequence of events controlling preadipocyte commitment and subsequent terminal differentiation into adipocytes is critical to gain insight into brown and white fat physiology and metabolic dysfunction. MicroRNAs (miRNAs) are important regulators of gene expression and emerging evidence supports their involvement in adipogenesis and adipose metabolism. The aim of this study is to 1) identify miRNAs that modulate differentiation or function of white and brown adi...

Improved knowledge of adipogenesis is necessary to gain insight into brown and white fat physiology. Interest in adipocyte differentiation has increased markedly over the past few years with emphasis on intersection between microRNAs (miRNAs) and the transcriptional cascade that controls adipogenesis and metabolic dysfunction. The aim of this study is to identify miRNAs that regulate white and brown adipocyte differentiation and define miRNA action in a stem cell model of adip...